Several upsets and a record four overtime games highlighted second round play at the NCAA men's basketball tournament.

No. 12 seed Harvard got 11 points from Siyani Chambers, including five straight in the final two minutes of a 61-57 upset of fifth-seed Cincinnati. Wesley Saunders scored 12 for the 27-4 Crimson who didn't trail after the opening minutes of the game. Harvard becomes the first Ivy League school with NCAA tourney wins in consecutive years since Princeton in 1983-84.

Harvard was another dangerous No. 12 seed. In 27 of the last 30 NCAA tournaments, the 12th seed has knocked off a five seed.

Cincinnati got 18 points from Sean Kilpatrick and finished 27-7.

In another 12-over-5 upset, the North Dakota State Bison upset Oklahoma 80-75 in overtime in the West region. It's the first-ever NCAA tournament victory for the Bison from Fargo. Lawrence Alexander hit a 3-pointer with 11 seconds left to force overtime and freshman Carlin Dupree scored four points in the final 75 seconds to seal it. Alexander hit for a career-high 28.

Cameron Clark led Oklahoma with 25.

Vee Sanford scored on a layup with 3.8 seconds left to lift 11th-seeded Dayton to a 60-59 victory over sixth-seeded Ohio State in Buffalo.

Sanford finished with 10 points, while Dyshawn Pierre led the 24-10 Flyers with 12 points in a matchup of Ohio schools separated by about 75 miles.

The Buckeyes (25-10) had one last chance to pull out the victory, but Aaron Craft's driving 10-footer hit off the backboard and rolled off the rim as the buzzer sounded.

Sam Thompson scored 18 points and Craft added 16 for Ohio State, which was eliminated after one game for only the third time in its 26 tournament appearances.

In other second-round tournament games:

— Florida, the top overall seed, got a tougher-than-expected test from 16th seed Albany before getting by the pesky Great Danes 67-55 in the South Region. Dorian Finney-Smith scored 16 points as the Gators ran their winning streak to 27.

— Michigan State, which is President Barack Obama's pick to win it all, got off to a fast start by beating 13th-seed Delaware 93-78 in the East region. Adreian Payne poured in a career-best 41 points for the fourth-seeded Spartans. He set an NCAA tournament record by making all 17 of his free throws.

— Defending national champion Louisville was all out to win its opener against upset-minded Manhattan. Luke Hancock launched two huge 3-pointers in the final two minutes to give the Cardinals a 71-64 win over the gutty Jaspers. Russ Smith led the Cardinals with 18.

— Ben Brust scored 17 points and Wisconsin devastated American with a 22-5 run to close the first half in a 75-35 victory. The second-seed Badgers trailed by seven points early in the game, but recovered to turn it into a rout. Wisconsin shot 57 percent in the second half to improve to 27-7.

— Guard Trevor Cooney scored 18 points and backcourt mate Tyler Ennis added 16 as Syracuse dumped Western Michigan 77-53. The 28-5 Orange forced 11 turnovers in the opening half and scored 13 points off them in running out to a double-digit lead before the midpoint of the period.

— Talib Zanna scored 16 of his 18 points in the opening half, helping Pittsburgh build a 28-point lead on the way to a 77-48 rout of Colorado. The Panthers shot 51 percent to improve to 26-9.

— Oregon held BYU to 33 percent shooting in running away from the Cougars 87-68 in the West Region. Elgin Cook scored a career-high 23 for the seventh-seeded Ducks.

— Connecticut, the seventh seed in the East, needed overtime to beat 10th-seed St. Joseph's 89-81. Shabazz Napier (shah-BAHZ' NAH'-pee-ayr) scored nine of his 24 points in OT.

— Saint Louis, the fifth seed in the Midwest, survived a scare from 11th-seed N.C. State before outlasting the Wolfpack 83-80 in OT. Jordair Jett scored 16 of his 17 points after the first half. Rob Loe scored 22 points and grabbed 15 rebounds.

— Glenn Robinson III scored 14 points, Jordan Morgan had 10 points and 10 rebounds, and the second-seeded Michigan Wolverines started their quest for a second straight trip to the Final Four by beating 15th-seeded Wofford (WAHF'-urd) 57-40.

— Texas, seventh seed in the Midwest, nipped Arizona State 87-85 on Cameron Ridley's buzzer-beating layup. Ridley finished with 17 points and 12 rebounds.

— Villanova, second seed in the East, ran away from Milwaukee 73-53. Darrun Hilliard scored 16 points and JayVaughn Pinkston added 13 for 'Nova.

— In the fourth overtime game of the day, fourth-seed San Diego State won a West regional second round game by beating New Mexico State 73-69. Xavier Thames (taymz) led the Aztecs with 23.

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